Comment on "Preserved feedforward but impaired top-down processes in the vegetative state".
نویسندگان
چکیده
Boly et al. (Reports, 13 May 2011, p. 858) investigated cortical connectivity patterns in patients suffering from a disorder of consciousness, using electroencephalography in an auditory oddball paradigm. We point to several inconsistencies in their data, including a failure to replicate the classical mismatch negativity. Data quality, source reconstruction, and statistics would need to be improved to support their conclusions.
منابع مشابه
Response to Comment on “Preserved Feedforward But Impaired Top-Down Processes in the Vegetative State”
Wethank King et al. (1) for deconstructing our paper (2) showing impaired top-down processes in the vegetative state (VS). We hope our responses provide some useful clarifications. (i) Regarding the number of patients, it would have been disappointing not to have found a common abnormality in eight well-defined VS patients. If we had needed 50 patients to obtain significant differences, we woul...
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Neuroimaging research has shown that subjects in vegetative state (or unresponsive wakefulness syndrome; VS/UWS) may retain high-level aspects of brain activity across sensory modalities, language and learning dynamics, emotions, or pain. Brain responses vary in complexity, from local activation of primary sensory cortices, to the involvement of associative areas, to activation of cortical–subc...
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عنوان ژورنال:
- Science
دوره 334 6060 شماره
صفحات -
تاریخ انتشار 2011